Cover Feature: Synthesis of Dihydroxyalkynyl and Dihydroxyalkyl Nucleotides As Building Blocks or Precursors for Introduction of Diol or Aldehyde Groups to DNA for Bioconjugations (chem. Eur. J. 46/2018)

A facile approach has been developed for enzymatic synthesis of DNA modified by reactive aldehyde groups which can be used for post-synthetic decoration of DNA through bioconjugations with peptides or other molecules. More information can be found in the Communication by M. Hocek, et al. on page 11890.