A New Era: Changing Patterns Of High-Grade Serous Fallopian Tube Cancer Diagnosis

Objective: Accumulating evidence suggests that the majority of nonuterine high-grade serous carcinomas (HGSC) of gynecologic origin are of fallopian tube rather than ovarian origin. We sought to explore the patterns of classification of diagnosis of HGSC relative to the establishment of the World Health Organization (WHO) guidelines for histopathologic classification of gynecologic malignancies (Kurman et al. 2014).