Should DTPA, an Aminocarboxylic acid (ethylenediamine-based) chelating agent, be considered a developmental toxicant?

Josje Arts,Steffen Bade, Marta Badrinas,Nicholas Ball,Stuart Hindle

Regulatory Toxicology and Pharmacology（2018）

Cited 10|Views8
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Abstract
Aminocarboxylic acid (ethylenediamine-based) chelating agents, such as DTPA and EDTA, are widely used in a variety of products and processes. Recently the European RAC proposed to classify DTPA as a developmental toxicant Category 1B according to CLP.
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Key words
Chelating agents,Zinc depletion,Developmental toxicity,Bioavailability
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