Magnetically Three-Dimensional Au Nanoparticles/Reduced Graphene/ Nickel Foams For Raman Trace Detection

Despite much effort has been done to improve the design of magnetic surface-enhanced Raman spectroscopy (SEAS) substrates, it still remains a great challenge to develop a clean and efficient substrate for quick and sensitive target detection incorporating with separation and enrichment. Herein, we proposed the synthesis of a three-dimensional structure of Au nanoparticles/reduced graphene oxide/nickel foams (AuNPs/rGO/NFs) for improving SEAS detection. The reduced graphene is firstly prepared on the surface of the nickel foams through surface reduction reaction, and then the Au NPs was formed in-situ on the rGO/NEs. Taking advantage of the magnetic properties of nickel foams, the adsorption of graphene and porous nickel foams, and hot spots of Au nanoparticles, the AuNPs/rGO/NFs-based SEAS assay can probe 4-pyridinethiol and 6-mercaptopurine as low as 5 x 10(-1) M.