Differentially Expressed Messenger RNA/proteins Can Distinguish Teratoma from Necrosis in Postchemotherapy Retroperitoneal Lymph Node Dissection Tissue.
Cancer(2022)
摘要
Before postchemotherapy retroperitoneal lymph node dissection (pcRPLND), in patients with metastasized germ cell tumors (GCTs), those harboring necrosis (NEC) cannot be distinguished from those who have teratoma (TER), resulting in relevant overtreatment, whereas microRNA‐371a‐3p may be predictive for viable GCT. The purpose of this study was to explore messenger RNA (mRNA) and proteins to distinguish TER from NEC in pcRPLND tissue.
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关键词
messenger RNA (mRNA),necrosis,postchemotherapy retroperitoneal lymph node dissection (pcRPLND),proteomics,teratoma,testicular germ cell tumor
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