3:36 PM Abstract No. 403 Midterm Outcomes in Terms of Impact on IPSS after Prostate Artery Embolization (PAE) for Benign Prostate Hyperplasia (BPH) with Lower Urinary Tract Symptoms (LUTS)

PAE is gaining acceptance as one of the treatment alternative for BPH with LUTS. We have successfully started the PAE program 3 years back. We have noted & reported that PAE is safe & effective in short-term with significant decrease in the IPSS. We would like to review sustenance of symptom improvement in midterm (6 mths) after PAE. In this retrospective study (2/2014-3/2017) 25 patients with 3- & 6-month follow-up were included. All the patients were consulted in the clinic and underwent a CTA of the pelvis, uroflow study (except catheter dependent) and labs. Patients’ pre- and postprocedure (3 & 6 mths) IPSS were recorded. All the patients received appropriate antibiotics and anti-inflammatory medicines. Embolizations were done using 100-300 micron TAG microspheres. All patients were followed up with 1 wk phone call by NP and 12 & 24 wks clinic visit with MRI pelvis. The adverse effects were also identified and classified according to the (CTCAE) V 4.0. Total number of patients 25 with median age 68 (47-82). The median time of procedure was 160 (60-350) minutes & the median fluoroscopic time was 43 (16-75) minutes. 1 pt required 1-day hospital admission. At 1 wk followup, 2 patients had perineal/perirectal pain not requiring pain medications. 1 pt developed transient hematuria and hematospermia. Median IPSS before PAE - 27 (6-35), at 3 mths-15 (3-28) & 6 mths-9 (2-32). The median and range of the individual IPSS scores are entered in the table. In this retrospective study, PAE appears to be safe and efficacious in short & midterm with progressive improvement in the IPSS at 6 mths without recurrence of the symptoms requiring other interventions. Major positive impact was noted on incomplete emptying and intermittency.Tabled 1Before PAE@ 3 Months@ 6 MonthsIncomplete emptying5(1-5)2(0-5)1(0-5)Frequency4(1-5)3(0-4)2(0-5)Intermittency5(0-5)2(0-2)1(0-4)Urgency4(0-5)2(0-4)1(0-5)Weak stream4(0-5)3(0-5)2(0-5)Straining2(1-5)1(0-3)1(0-5)Nocturia3(1-5)2(0-4)1(0-5) Open table in a new tab