Rational design and fabrication of multiphasic soft network composites for tissue engineering articular cartilage: A numerical model-based approach
Chemical Engineering Journal(2018)
摘要
•Composites consisting of a hydrogel matrix and 3D printed microfibers are developed.•An in silico design library based on a numerical model is presented.•The library has good prediction capabilities and can accelerate the design process.•Multiphasic composites that mimic articular cartilage are developed for validation.
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关键词
Soft network composites,Melt electrospinning writing,Articular cartilage,Rational design,Gelatin methacryloyl,Multiphasic,3D printing,Soft tissue engineering,Fibers
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