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Ortho group activation of a bromopyrrole ester in Suzuki-Miyaura cross-coupling reactions: Application to the synthesis of new microtubule depolymerizing agents with potent cytotoxic activities

John T. Gupton,Scott Yeudall,Nakul Telang,Megan Hoerrner, Ellis Huff,Evan Crawford, Katie Lounsbury,Michael Kimmel, William Curry,Andrew Harrison,Wen Juekun,Alex Shimozono,Joe Ortolani,Kristin Lescalleet,Jon Patteson,Veronica Moore-Stoll,Cristina C. Rohena,Susan L. Mooberry,Ahmad J. Obaidullah,Glen E. Kellogg,James A. Sikorski

Bioorganic & Medicinal Chemistry（2017）

引用 4|浏览16
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关键词
Suzuki-Miyaura cross-coupling,Pyrrole,Microtubule inhibitors,Marine natural products,Cytotoxic activity
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