Liquid Biopsies: Non-Invasive Rejection Detection After Heart Transplantation

After heart transplantation (HTx) acute cellular rejection (ACR) can damage the allograft which leads to the release of donor cell free DNA (cfDNA) into the circulation of the recipient. The amount of donor cfDNA in the recipients blood (liquid biopsies) can be measured using digital PCR. The aim of our study is to implement this non-invasive liquid biopsy technique for donor cfDNA detection post-HTx.