AB0450 Systemic Lupus Erythematosus: A French Experience for 6 Years of Multidisciplinary Consultation in Brest

Background Systemic lupus erythematosus (SLE) is a complex disease and its diagnosis and treatment can require multiple capabilities easily available for the patients. Objectives Our objective was to set up a multidisciplinary consultation enabling patient support in occidental Brittany. Methods Given the complexity for the management of patients with systemic lupus erythematosus (SLE), a multidisciplinary consultation was set up to ensure optimal care for SLE patients at Brest University Medical School. This consultation was set on a quarterly base and gather rheumatologists, dermatologists, nephrologists, gynecologists and internal medicine physicians. A close collaboration with the immunology laboratory for biological diagnosis and follow-up was also set up. Clinical and biological data were collected. Results Of the 49 SLE patients followed since 2009, 45 were women (91.8%). The mean age was 47.1±17.7 years. Eighteen patients had malar rash (37.5%), 21 (43.8%) photosensitivity, 7 (14.6%) oral ulcers, 6 (12.5%) alopecia, 43 (89.6%) diffuse articular pain or arthralgia, 10 (20.8%) tenosynovitis, 15 (31.25%) lupus glomerulonephritis, 7 (14.3%) pericarditis, 2 (4%) cardiac vegetations, and 3 (6.1%) pleurisy. The mean SLEDAI score was 2.7±3.5, with values ranging from 0 to 17. Twenty patients were referred for diagnostic opinions (40.8%), 31 (63.3%) for therapeutic advice, 3 (6%) for pregnancy monitoring, and 16 (32.6%) for comorbidities management. The main comorbidities were cardiovascular risk factors and osteoporosis. Conclusions In conclusion, the multidisciplinary consultation helps to provide diagnostic and therapeutic aid due to the presence of experts from several disciplines. Patient enrollment for several services enables the creation of a valuable database whose analysis is ongoing. Disclosure of Interest None declared