Evaluating effect of cardiac resynchronization therapy in patients with dilated cardiomyopathy by tissue synchromization imaging

Objective Cardiac resynchronization therapy(CRT) by simultaneous biventricular pacing improves left ventricular systolic synchrony in patients with dilated cardiomyopathy(DCM). Tissue synchronization imaging(TSI) technique was used to evaluate the impact of sequential CRT with individualized interventricular delay programming.Methods TSI was carried out in five patients with DCM and left bundle branch block before and one day after pacemaker implantation in four chamber view,two chamber view and apical long aixs view and in two patients with DCM before pacemaker implantation.Results Three patients with DCM showed that left ventricular asynchrony was improved afetr CRT,but two patients with DCM showed left ventricular asynchrony was not improved after CRT.CRT was not performed in one patient with DCM due to ventricular systolic resynchronization,one patient with DCM did not have CRT because LVEF was 42%.Conclusions TSI is useful in predicting and evaluating the effect of CRT in the patients with DCM.