NANO-COPPER CATALYZED THREE-COMPONENT TANDEM CYCLOADDITION AND N-ALKYLATION REACTION FROM AMINOPHENYLACETYLENES, SODIUM AZIDE AND ALKYL HALIDES

HETEROCYCLES（2015）

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摘要

Nano-copper catalyzed one-pot three-component method is realized from aminophenylacetylenes, sodium azide and alkyl halides via tandem 3+2 dipolar cycloaddition reaction and N-alkylation reaction. This synthetic process gave the product of 1-alkyl-4-(N-alkylaminophenyl)-1H-1,2,3-triazoles in good yields.

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关键词

Nano-Copper Catalysis,Cycloaddition Reaction,N-Alkylation Reaction,Tandem Reaction,Multicomponent Reaction

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