Efficient tin-mediated synthesis of lysophospholipid conjugates of a TLR7/8-active imidazoquinoline
Tetrahedron Letters(2016)
摘要
•A new protocol for the lysophosphatidylation of alcohols is reported.•It involves the tin-mediated regioselective acylation of a glycerol intermediate.•It is applied to the lysophosphatidylation of TLR7/8-active imidazoquinolines.
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关键词
TLR7/8,Imidazoquinoline,Lysophospholipids
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