Effects of the Multiple O-glycosylation States on Antibody Recognition of the Immunodominant Motif in MUC1 Extracellular Tandem Repeats

Shobith Rangappa,Gerard Artigas,Risho Miyoshi,Yasuhiro Yokoi,Shun Hayakawa,Fayna Garcia-Martin,Hiroshi Hinou,Shin-Ichiro Nishimura

MedChemComm（2016）

引用 26|浏览14

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摘要

The conformational impact of the clusteredO-glycans strongly influences recognition by antibodies of the cancer-relevant epitope in the MUC1 extracellular tandem repeat domain.

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