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Could renin-angiotensin-aldosterone system activation explain the amputations associated with canagliflozin? the nitric oxide hypothesis.

David León Jiménez,José Manuel López Chozas,Antonio Espino Montoro,Miguel Ángel Rico Corral,Luis Castilla Guerra,José Pablo Miramontes González

Diabetes Research and Clinical Practice（2019）

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ACE,ACEi,ACE2,ANG,BK,DM,ED,eNOs,FAERS,NO,RAAS,SGLT2i
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