Isoindolinone Compounds Active As Kv1.5 Blockers Identified Using A Multicomponent Reaction Approach

Johan Kajanus,Ingemar Jacobson,Annika Astrand,Roine I. Olsson,Ulrik Gran,Annika Bjore,Ola Fjellstrom,Ojvind Davidsson,Hans Emtenas,Anders Dahlen,Boel Lofberg,Zhong-Qing Yuan,Johan Sundell,Johan Cassel,Jonna Gyll,Tommy Iliefski,Agot Hogberg,Emma Lindhardt,Jesper Malmberg

Bioorganic & medicinal chemistry letters（2016）

引用 16|浏览41

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关键词

Atrial fibrillation,Kv1.5,IKur,Isoindolinones,Multicomponent reactions,Structure activity relationship (SAR)

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