Association between ADAM12 polymorphism and knee osteoarthritis in Thai population

•The significant associations were shown from the C allele in male knee OA patients.•The CC genotype in male OA patients seemed to exhibit higher risk of knee OA than the GG genotype.•The rs3740199 in ADAM12 was not associated with the susceptibility of knee OA in the females.•The rs3740199 in ADAM12 was associated with knee OA susceptibility in Thai male patients.