Seizures occurring while driving in patients with and without diagnosis of epilepsy: Frequency and association with automobile accidents

•Seizure may occur during any human activity, including driving.•A study was conducted to report the frequency of seizure occurring while driving.•Among 658 adult seizure patients, 19 (2.9%) sustained a seizure while driving.•Frequency of seizure did not differ between patients with and those without epilepsy.•Sixteen of the 19 drivers sustaining a seizure (84%) caused automobile accidents.