Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion.
JOURNAL OF MOLECULAR ENDOCRINOLOGY(2019)
关键词
pancreatic beta-cells,secretory granules,proinsulin/insulin secretion,glucose signaling,protein sorting,guanine nucleotide exchange factor (GEF),Kalirin,Trio,Ras-related C3 botulinum toxin substrate 1 (Rac1),serine/threonine-protein kinase PAK 1 (PAK1),CDC42
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