Descriptive report of cases of congenital syndrome associated with Zika virus infection in the state of São Paulo, Brazil, from 2015 to 2017.

Objective: to characterize cases of congenital syndrome associated with Zika virus infection (CZS) and other infectious etiologies, resident in the state of Sao Paulo, Brazil, from October 30, 2015, to June 30, 2017. Methods: this was a descriptive study of suspected cases of CZS and other infectious etiologies notified on the Public Health Events Registry. Results: 960 cases were investigated up to epidemiological week 26/2017, and 146 were confirmed for congenital infection; of these, 59 (40.4%) were confirmed for congenital infection without etiological identification and 87 (59.6%) with laboratory confirmation, of which 55 were congenital syndrome associated with Zika virus and 32 were congenital syndrome associated with other infectious agents. Conclusion: this study enabled the detection of 23.9% CZS cases among suspected cases of infectious etiology.