Ovulation induction strategies in polycystic ovary syndrome.

We thank Levin and Rottenstreich for their interest in our article on ovulation induction strategies in polycystic ovary syndrome (PCOS). We suggested as a second line treatment after life style changes, the combination of inositol isomers and metformin or metformin only. The use of inositol was primarily based on the results of a systematic review by Pundir et al., although other small studies not included in the systematic review have also indicated a possibly beneficial effect on ovulation in anovulatory PCOS. This article is protected by copyright. All rights reserved.