The PDE6 Mutation in the Rd10 Retinal Degeneration Mouse Model Causes Protein Mislocalization and Instability and Promotes Cell Death Through Increased Ion Influx.
Journal of biological chemistry/The Journal of biological chemistry（2018）
关键词
photoreceptor,phosphodiesterases,cyclic GMP (cGMP),retinal degeneration,phototransduction,cell death,protein translocation,protein stability,cGMP-gated channels,missense mutation,PDE6,protein transport,protein mislocalization
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