Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841).Andrew Fensome,Catherine M. Ambler,Eric Arnold,Mary Ellen Banker,Matthew F. Brown,Jill Chrencik,James D. Clark,Martin E. Dowty,Ivan V. Efremov,Andrew Flick,Brian S. Gerstenberger,Ariamala Gopalsamy,Matthew M. Hayward,Martin Hegen,Brett D. Hollingshead,Jason Jussif,John D. Knafels,David C. Limburg,David Lin,Tsung H. Lin,Betsy S. Pierce,Eddine Saiah,Raman Sharma,Peter T. Symanowicz,Jean-Baptiste Telliez,John I. Trujillo,Felix F. Vajdos,Fabien Vincent,Zhao-Kui Wan,Li Xing,Xiaojing Yang,Xin Yang,Liying ZhangJournal of Medicinal Chemistry（2018）引用 102|浏览53暂无评分关键词cytokine signaling,Inflammatory Cytokines,Inflammation,Immune ResponsesAI 理解论文溯源树样例生成溯源树，研究论文发展脉络Chat Paper正在生成论文摘要
