Exploration of Pyrrolobenzodiazepine(PBD)-dimers Containing Disulfide-based Prodrugs as Payloads for Antibody-Drug Conjugates.
Zhonghua Pei,Chunjiao Chen,Jinhua Chen,Josefa Dela Cruz-Chuh,Reginald Delarosa,Yuzhong Deng,Aimee Fourie-O'Donohue,Isabel Figueroa, Jun Guo, Weiwei Jin,S Cyrus Khojasteh,Katherine R Kozak,Brandon Latifi,James Lee,Guangmin Li,Eva Lin,Liling Liu,Jiawei Lu,Scott Martin,Carl Ng,Trung Nguyen,Rachana Ohri,Gail Lewis Phillips,Thomas H Pillow,Rebecca K Rowntree,Nicola J Stagg,David Stokoe,Sheila Ulufatu,Vishal A Verma,John Wai,Jing Wang,Keyang Xu,Zijin Xu,Hui Yao,Shang-Fan Yu,Donglu Zhang,Peter S Dragovich MOLECULAR PHARMACEUTICS(2018)
关键词
prodrug,disulfide,antibody-drug conjugate,pyrrolobenzodiazepine
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