5-hydroxymethylfurfural- and Fluorescein- Fused Fluorescence Probe of Mast Cells (RBL-2H3): Synthesis, Photophysical Properties and Bioimaging.
CHEMICAL BIOLOGY & DRUG DESIGN(2018)
摘要
A fluorescent probe (Fluo-HMF) was developed via introduction of a furfural moiety into the fluorescein molecular skeleton, aiming at specially labeling cell membrane of mast cells. To illustrate its specificity, we designed and synthesized a series of fluorescent compounds based on fluorescein molecular skeleton. The fluorescent properties of Fluo-HMF were investigated, which were in accordance with theoretical calculations. Compared with other fluorescein derivatives, Fluo-HMF could specially label RBL-2H3 cells. The results suggested that Fluo-HMF could be used as a fluorescent probe for bioimaging on some related research of allergic mechanism.
更多查看译文
关键词
bioimaging,Fluo-HMF,fluorescent probe,RBL-2H3 cells,theoretical calculation
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要