Erythropoietin-mediated activation of aquaporin-4 channel for the treatment of experimental hydrocephalus.

M Rizwan Siddiqui, Furqan Attar, Vineet Mohanty,Kwang Sik Kim,C Shekhar Mayanil,Tadanori Tomita

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery（2018）

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摘要

Together, our results show that EPO-mediated upregulation of AQP4 significantly reduces dilation of the cerebral ventricles in obstructive hydrocephalus pups and may lead to potential therapeutic options for hydrocephalus.

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关键词

Aquaporin water channel,Erythropoietin,Hydrocephalus,MicroRNA

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