Effect of Resveratrol and Metformin on Ovarian Reserve and Ultrastructure in PCOS: an Experimental Study

Selenay Furat Rencber, Sema Kurnaz Ozbek,Ceyla Eraldemır,Zehra Sezer,Tugba Kum,Sureyya Ceylan,Elif Guzel

Journal of Ovarian Research（2018）

引用 141|浏览4

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摘要

PCOS is a reproductive hormonal abnormality and a metabolic disorder. It is frequently associated with insulin resistance, hyperandrogenism, chronic inflammation, and oxidative stress. We aim to investigate the potential therapeutic effects of combined therapy of resveratrol and metformin on polycystic ovaries via SIRT1 and AMPK activation.

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关键词

Dehydroepiandrosterone,Resveratrol,Metformin,Polycystic ovary syndrome,Oxidative stress,Inflammation

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