Madeira moneywort (Sibthorpia peregrina L.) as a new source of verbascoside and its derivatives with potential phyto-pharmaceutical applications
Natural Product Research(2019)
摘要
The qualitative and quantitative characterization of Madeira moneywort (Sibthorpia peregrina L.) compounds was investigated for the first time. The antioxidant activity and the effect of the methanolic extract on digestive enzymes activity linked to type-2 diabetes and obesity were also determined by in vitro assays. A total of 56 components were characterized in S. peregrina. Phenylethanoids glycosides (PhEGs) represented the main classes of compounds (95.23 mg g−1 of dry extract), almost all verbascoside and its derivatives (up to 98.85% of the total individual phenolic content). The analysed sample was active against ABTS, DPPH, nitric oxide and superoxide radicals, suggesting a potential beneficial effect against oxidative stress. In addition, the methanolic extract was able to inhibit the catalytic activity of α-, β-glucosidases, α-amylase and pancreatic lipase. Overall, S. peregrina showed good perspectives to be explored as a rich source of verbascoside and its derivatives for nutraceutical/pharmaceutical products.
更多查看译文
关键词
Sibthorbia peregrina L.,Madeira moneywort,phenolic composition,verbascoside,antioxidant activity,digestive enzymes inhibition
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要