Control of Heterologous Simian Immunodeficiency Virus SIVsmE660 Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques.
Journal of virology（2018）
关键词
DNA,protein,TLR4,TLR7,QS21,adjuvant,rhesus macaque,vaccination,vaccine,immunization,SIVmac251,SIVsmE660,HIV,SIVsmE660 T/F,A/K variant,TRIM-5 alpha,humoral responses,binding antibody,neutralizing antibody,linear peptide,cyclic V2,scaffolded gp70-V1V2,ADCC,ADCD,ADNP,Ab glycosylation structures,T cell responses,mucosal responses,repeated low-dose rectal challenge,reduced risk of infection,viremia control,correlate of viremia control,V2 responses,acquisition delay,systems serology
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