Longevity and Pleural Mesothelioma: Age-Period-cohort Analysis of Incidence Data from the Surveillance, Epidemiology, and End Results (SEER) Program, 1973–2013

This study investigates the hypothesis that an increasing fraction of incident pleural mesothelioma (PM) in the US population may be related to longevity, i.e., to expansion of the population over age 75 years with an age-related elevation in risk. An age-period-cohort analysis of the SEER 9 cancer registries (1973–2013) was conducted using 5-year intervals of age, calendar period, and birth cohort after stratification into four gender-age groups (male and female; 0–74 and 75+ years).