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The Discovery and Preclinical Evaluation of BMS-707035, a Potent HIV-1 Integrase Strand Transfer Inhibitor.

B. Narasimhulu Naidu,Michael A. Walker,Margaret E. Sorenson,Yasutsugu Ueda,John D. Matiskella,Timothy P. Connolly,Ira B. Dicker,Zeyu Lin,Sagarika Bollini,Brian J. Terry,Helen Higley,Ming Zheng,Dawn D. Parker,Dedong Wu,Stephen Adams,Mark R. Krystal,Nicholas A. Meanwell

Bioorganic & Medicinal Chemistry Letters（2018）

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关键词
HIV-1 integrase,Strand transfer inhibitors,INSTI,Pyrimidinone carboxamides,Antiviral activity,Pharmacokinetics
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