Reconsideration of the immunotherapeutic pediatric safe dose levels of aluminum.

•Aluminum levels in vaccine is based on immune efficacy and ignore body weight for safety.•Several critical mistakes have been made in the consideration of pediatric dosing of aluminum in vaccines.•Safety inferences of vaccine doses of aluminum have relied solely on dietary exposure studies of adult mice and rats.•On Day 1 of life, infants receive 17 times more aluminum than would be allowed if doses were adjusted per body weight.•Revised MRL calculation based weights are provided, but are also based on derived speculation, not on safety data.