Burst-Like Transcription of Mutant and Wildtype MYH7-Alleles As Possible Origin of Cell-to-Cell Contractile Imbalance in Hypertrophic Cardiomyopathy

Judith Montag,Kathrin Kowalski,Mirza Makul,Pia Ernstberger,Ante Radocaj,Julia Beck,Edgar Becker,Snigdha Tripathi,Britta Keyser,Christian Muhlfeld,Kirsten Wissel,Andreas Pich,Jolanda van der Velden,Cristobal G. dos Remedios,Andreas Perrot,Antonio Francino, Francesco Navarro-Lopez,Bernhard Brenner,Theresia Kraft

Frontiers in Physiology（2018）

引用 43|浏览32

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关键词

hypertrophic cardiomyopathy,human cardiomyocytes,single-cell allelic imbalance,ventricular myosin heavy chain,myosin mutations,burst-like transcription

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