Exposure to endocrine disruptors 17alpha-ethinylestradiol and estradiol influences cytochrome P450 1A1-mediated genotoxicity of benzo[a]pyrene and expression of this enzyme in rats.
Toxicology(2018)
摘要
Effects of 17α-ethinylestradiol (EE2) and estradiol (ESTRA) on DNA adducts formed by benzo[a]pyrene (BaP).
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关键词
AhR,BaP,BPDE,COMT,CYP,EE2,DMSO,ED,dG-N2-BPDE,EROD,GAPDH,NADPH,mEH,NQO1,PAH,POR,TLC,RAL
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