Hif Activation Causes Synthetic Lethality Between The Vhl Tumor Suppressor And The Ezh1 Histone Methyltransferase

Abhishek A Chakraborty,Eijiro Nakamura,Jun Qi,Amanda Creech,Jacob D Jaffe,Joshiawa Paulk,Jesse S Novak,Kshithija Nagulapalli,Samuel K McBrayer,Glenn S Cowley,Javier Pineda,Jiaxi Song,Yaoyu E Wang,Steven A Carr,David E Root,Sabina Signoretti,James E Bradner,William G Kaelin

SCIENCE TRANSLATIONAL MEDICINE（2017）

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关键词

histone methyltransferase,hif activation,tumor suppressor,synthetic lethality

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