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Derivatization of inhibitor of apoptosis protein (IAP) ligands yields improved inducers of estrogen receptor α degradation

Nobumichi Ohoka,Yoko Morita,Katsunori Nagai,Kenichiro Shimokawa,Osamu Ujikawa,Ikuo Fujimori,Masahiro Ito, Youji Hayase,Keiichiro Okuhira,Norihito Shibata,Takayuki Hattori,Tomoya Sameshima,Osamu Sano,Ryokichi Koyama,Yasuhiro Imaeda,Hiroshi Nara,Nobuo Cho,Mikihiko Naito

Journal of Biological Chemistry（2018）

引用 86|浏览36
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关键词
ubiquitin,proteasome,X-linked inhibitor of apoptosis protein (XIAP),estrogen receptor,tumor therapy,SNIPER,protein knockdown,ERalpha
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