Living Up to the Hype: Protein Synthesis Promotes Hypertranscription in Embryonic Stem Cells.
Cell Stem Cell（2018）
摘要
The rapid proliferation and unlimited self-renewal of embryonic stem cells depends upon a permissive chromatin landscape that enables hypertranscription. In this issue of Cell Stem Cell, Bulut-Karslioglu et al. report that euchromatin and transcriptional output are enhanced by protein synthesis in embryonic stem cells (Bulut-Karslioglu et al., 2018).
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