Elevated intragraft expression of innate immunity and cell death-related markers is a risk factor for adverse graft outcome.

Jianxin Yang,Malou L H Snijders,Geert W Haasnoot,Cees van Kooten,Marko Mallat,Johan W de Fijter,Marian C Clahsen-van Groningen,Frans H J Claas,Michael Eikmans

Transplant Immunology（2018）

引用 5|浏览15

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摘要

•Deceased donors have increased complement expression and Bax:Bcl2 ratio•High Bax:Bcl2 ratio in rejecting deceased donors predicts inferior graft survival.•High TLR4 expression in rejecting deceased donors predicts inferior graft survival.

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关键词

Toll like receptors,Complement,Apoptosis,Gene expression,Kidney transplant outcome

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