Stapled truncated orexin peptides as orexin receptor agonists.
Peptides(2018)
摘要
•Peptide stapling of the neuropeptide orexin‐A15–33 lowers the potency significantly.•The peptide C-terminus is crucial for activity, and modifications were not allowed.•Central and N‐terminal modifications yielded bioactive peptides.
更多查看译文
关键词
Aib,Fmoc,HPLC,HBM
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要