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Facile Synthesis, Geometry, and 2 '-Substituent-dependent in Vivo Activity of 5 '-(E)- and 5 '-(Z)-vinylphosphonate-modified Sirna Conjugates

Rubina Giare Parmar,Christopher R. Brown,Shigeo Matsuda,Jennifer L. S. Willoughby,Christopher S. Theile,Klaus Charisse,Donald J. Foster,Ivan Zlatev,Vasant Jadhav,Martin A. Maier,Martin Egli,Muthiah Manoharan,Kallanthottathil G. Rajeev

Journal of medicinal chemistry（2018）

Cited 34|Views59
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