Comparative Analysis of Lactic Acidosis Induced by Linezolid and Vancomycin Therapy Using Cohort and Case–control Studies of Incidence and Associated Risk Factors

Nobuaki Mori, Yoshio Kamimura,Yuki Kimura,Shoko Hirose,Yasuko Aoki,Seiji Bito

European journal of clinical pharmacology（2017）

引用 8|浏览13

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摘要

Lactic acidosis is a rare complication of linezolid (LZD) therapy, and its incidence and risk factors remain unknown. This study aimed to compare the incidence of LZD-associated lactic acidosis (LALA) and vancomycin (VAN)-associated lactic acidosis (VALA) and investigate the risk factors for LALA.

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关键词

Linezolid-associated lactic acidosis,Vancomycin-associated lactic acidosis,Propensity score-matched analysis,Renal insufficiency

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