Role of PDGF-BB in proliferation, differentiation and maintaining stem cell properties of PDL cells in vitro.

Zornitsa Mihaylova,Rozaliya Tsikandelova, Pavel Sanimirov,Natalia Gateva,Vanyo Mitev,Nikolay Ishkitiev

Archives of Oral Biology（2018）

引用 35|浏览6

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摘要

•Mesenchymal stem cells from human PDL were isolated and characterized.•Cells were treated with PDGF-BB.•Cell proliferation rate was increased after PDGF-BB treatment.•PDGF-BB stimulates collagen chains maturation and inhibits mineralization.•PDGF-BB supports stem cell properties.

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关键词

Platelet-derived growth factor,Periodontal ligament,Mesenchymal stem cells

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