Balancing Selectivity and Efficacy of Bispecific Epidermal Growth Factor Receptor (EGFR) × c-MET Antibodies and Antibody-Drug Conjugates

Carolin Sellmann,Achim Doerner,Christine Knuehl,Nicolas Rasche,Vanita Sood,Simon Krah,Laura Rhiel, Annika Messemer,John Wesolowski,Mark Schuette,Stefan Becker,Lars Toleikis,Harald Kolmar,Bjoern Hock

Journal of Biological Chemistry（2016）

引用 58|浏览26
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关键词
antibody engineering,anticancer drug,epidermal growth factor receptor (EGFR),sortase A,toxicity
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