A New Furanocoumarin from the Roots of Angelica Oncosepala
Chemistry of natural compounds(2012)
摘要
A new furanocoumarin oncosepalin A (1), together with two known compounds, ferulic acid and β-sitosterol, was isolated from the roots of Angelica oncosepala. The structure of the new compound was elucidated by spectroscopic methods, including extensive 1D and 2D NMR experiments, as well as high-resolution EI mass analysis. Compound 1 showed cytotoxic inhibition against HL-60 human tumor cell lines with an IC50 value of 2.04 μM.
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关键词
Angelica oncosepala,furanocoumarin,cytotoxicity,oncosepalin A
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