Synthesis of 3-Methyl-3,4-dihydroisoquinolines Based on Myristicin

The reaction of a natural allylbenzene, myristicin, with nitriles afforded a series of 7,8-dihydro-[1,3]dioxolo[4,5- g ]isoquinoline and 6,7-dihydro[1,3]dioxolo[4,5- h ]isoquinoline derivatives.