MicroRNA181a regulates Osteopontin expression and cardiac fibrosis in mice
Journal of the American College of Cardiology(2016)
摘要
Osteopontin (OPN) is a secreted glycophosphoprotin that has been shown to play an important role in cardiac fibrosis and remodeling. Here our objective was to determine whether microRNA181a would regulate OPN expression and cardiac fibrosis in mice. cardiac fibroblast cells isolated from adult
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关键词
microrna181a,cardiac fibrosis,osteopontin expression
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