Nanoencapsulated budesonide in self-stratified polyurethane-polyurea nanoparticles is highly effective in inducing human tolerogenic dendritic cells

Georgina Flórez-Grau,Pau Rocas,Raquel Cabezón,Carolina España,Julián Panés,Josep Rocas,Fernando Albericio,Daniel Benítez-Ribas

International Journal of Pharmaceutics（2016）

引用 15|浏览11

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摘要

The design of innovative strategies to selectively target cells, such antigen-presenting cells and dendritic cells, in vivo to induce immune tolerance is gaining interest and relevance for the treatment of immune-mediated diseases.

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APCs,Bayhydur 3100,BDS,DCs,DiI,IL-,MLR,PBMCs,PBLs,PUUa NPs,PUUa NPs-BDS,PUUa NPs-DiI,YMER N-120,Tol-DCs,TNFα

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