Therapeutic potential of spinal GLP-1 receptor signaling.

Peptides（2018）

引用 6|浏览10

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摘要

•We summarized the expression of GLP-1R and the innervation of PPG neurons in the spinal cord.•Stimulation of GLP-1R within the spinal cord promotes neuroprotection in specific neurodegenerative and traumatic spinal cord disorders.•Activating GLP-1R in spinal microglia cells suppresses nociceptive sensitization.

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关键词

GLP-1,GLP-1R,DPP-4,T2DM,CNS,PPG,NTS,ALS,SCI,YFP,MS,EAE,SOD1,ChAT,GFAP

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