Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases Michael L. Vazquez , Neelu Kaila , Joseph W. Strohbach , John D. Trzupek , Matthew F. Brown , Mark E. Flanagan , Mark J. Mitton-Fry , Timothy A. Johnson , Ruth E. TenBrink , Eric P. Arnold , Arindrajit Basak , Steven E. Heasley , Soojin Kwon , Jonathan Langille , Mihir D. Parikh , Sarah H. Griffin , Jeffrey M. Casavant , Brian A. Duclos , Ashley E. Fenwick , Thomas M. Harris , Seungil Han , Nicole Caspers , Martin E. Dowty , Xin Yang , Mary Ellen Banker , Martin Hegen , Peter T. Symanowicz , Li , Lu Wang , Tsung H. Lin , Jason Jussif , James D. Clark , Jean-Baptiste Telliez , Ralph P. Robinson , Ray Unwalla Journal of Medicinal Chemistry(2018)
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