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AMP-activated protein kinase (AMPK) is decreased in the mouse brain during experimental cerebral malaria

Neuroscience Letters(2018)

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摘要
•First study on the status of AMPK in brain during murine cerebral malaria.•Reduction in gene expression of AMPK catalytic subunits α1 and α2.•Reduction in protein levels of activated AMPK.•AMPK activating drugs might decrease morbidity associated with cerebral malaria.
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关键词
Plasmodium berghei ANKA,AMP-activated protein kinase,AMPK,Experimental cerebral malaria
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